Fillers are used to plump or fill in a fine line or wrinkle as well as contour and change the shape of an area. Most fillers are made of hyaluronic acid (HA), which is a natural precursor of collagen. Thus, your body puts collagen and water over the top of them enhancing their effectiveness and creating improvement for up to 6 weeks. They vary in thickness and some are thin such as Belotero which can be used under the eye and lasts 6-9 months or Volbella which is also thin and can be used in the fine lines above the lip or other very fine-lined areas. Juvederm Ultra and Ultra Plus are medium thickness fillers that last 9-12 months. They are best used for larger areas of depression such as smile lines, chin creasing, and lips. The thickest fillers of the group and Voluma and Radiesse. Voluma is a workhorse and can be used to lift and contour cheeks and jawlines, for non-surgical nose jobs and in the deeper creases of the smile lines. Radiesse is the only filler that is non-hyaluronic acid. It is calcium hydroxylapatite which has been shown to still produce collagen and is good for patients that tend to break down the other type of fillers (HA) or need extra lift due to severe volume loss.